Two distinct mechanisms underlying t cell-mediated regulation of collagen type i in lung fibroblasts

HIGHLIGHTS

• who: Daisuke Okuno et al. from the Department of Respiratory Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan have published the Article: Two Distinct Mechanisms Underlying T Cell-Mediated Regulation of Collagen Type I in Lung Fibroblasts, in the Journal: Cells 2022, 2816 of /2022/
• what: The authors aimed to develop a novel cell-based therapy for IPF. The authors demonstrated that PTA/IL-2-expanded u03b3u03b4 T_cells expressed high LFA-1 levels. Despite these limitations, this study provides considerable insight into the development of u03b3u03b4 T_cell-based immunotherapies for lung fibrosis.
 



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