Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3 9 -end antisense transcription

HIGHLIGHTS

  • who: Transcription et al. from the Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands, Marseille Cancer Research Center (CRCM), Inserm, CNRS, AixMarseille Université, Institut Paoli-Calmettes, Marseille, France, Institut Jacques Monod, Université Paris Diderot, CNRS, Paris, France have published the research work: Two Distinct Repressive Mechanisms for Histone 3 Lysine 4 Methylation through Promoting 3 9 -End Antisense Transcription, in the Journal: (JOURNAL) of September/20,/2012
  • what: The authors investigate the functional effects of each H3K4 methylation state on transcription. The authors show that there are two separate mechanisms through which H3K4 . . .

     

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