HIGHLIGHTS
- who: Junichi Nakai from the (UNIVERSITY) have published the research: Two Regions of the Ryanodine Receptor Involved in Coupling withl-Type Ca2+ Channels*, in the Journal: (JOURNAL) of February/17,/1998
SUMMARY
To "receiving" the EC coupling signal from the DHPR, RyR-1 also "transmits" a retrograde signal that enhances the Ca21 channel activity of the DHPR (Nakai, J. To investigate the molecular mechanism of reciprocal signaling, the authors constructed cDNAs encoding chimeras of RyR-1 and RyR-2 (the predominant cardiac RyR isoform) and expressed them in dyspedic myotubes, which lack an . . .
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