Two small-molecule activators share similar effector sites in the kcnq1 channel pore but have distinct effects on voltage sensor movements

HIGHLIGHTS

• who: . et al. from the Centres (HZ), Germany University of California, Davis have published the paper: Two small-molecule activators share similar effector sites in the KCNQ1 channel pore but have distinct effects on voltage sensor movements, in the Journal: (JOURNAL)
• what: This model has 12 states, corresponding to closed and open states for four independent voltage sensing domains with a final concerted opening step as published previously (Peng Frontiers in Physiology frontiersin.org 10.3389/fphys.2022.903050 cytometry using the BD LSRII Cell Analyzer (BD Biosciences, San Jose, CA, United_States). In Figure 4 . . .
  

   

  

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