Txh11106: a third-generation mreb inhibitor with enhanced activity against a broad range of gram-negative bacterial pathogens

HIGHLIGHTS

• who: Eric J. Bryan et al. from the Department of Pharmacology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USADepartment of Molecular Design and Synthesis, Rutgers University Biomedical Research Innovation Cores have published the research: TXH11106: A Third-Generation MreB Inhibitor with Enhanced Activity against a Broad Range of Gram-Negative Bacterial Pathogens, in the Journal: Antibiotics 2022, 693 of /2022/
• what: The authors show that the third-generation MreB inhibitor TXH11106 is associated with enhanced bactericidal activity against the clinically significant Gram-negative pathogens E. coli, K. pneumoniae, A. baumannii, and P. aeruginosa relative . . .
  

   

  

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