Tyk2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits

HIGHLIGHTS

  • who: Dorothée Diogo et al. from the School, Boston, Massachusetts, United of America, Division of Genetics, Brigham and Women's , Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, United of have published the paper: TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0122271]. April 7, 2015 of /1371/
  • what: The authors show that the same three systemic lupus erythematosus (SLE Pomnibus = 6x10-18) and provide suggestive evidence that two of . . .

     

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