HIGHLIGHTS
- who: MDPI from the State Key Laboratory of Genetic Engineering, School of Life Science, Fudan University, Shanghai, China have published the article: Type of the Paper (Article, in the Journal: Microorganisms 2022, 10, 2473. of 14/Dec/2022
- what: Based on the data , the authors propose that M. tuberculosis PE_PGRS19 triggers cell pyroptosis by activating the non-canonical caspase-11-GSDMD-IL-1u03b2/18 pathway, which might also benefit the dissemination of bacteria in granulomas and contribute to the spread of bacteria to surrounding cells, representing a novel pathway elicited by the PE/PPE family . . .
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