Type xvii collagen: relevance of distinct epitopes, complement-independent effects, and association with neurological disorders in pemphigoid disorders

HIGHLIGHTS

• who: Bianca Opelka et al. from the Rush University, United States have published the paper: Type XVII collagen: Relevance of distinct epitopes, complement-independent effects, and association with neurological disorders in pemphigoid disorders, in the Journal: (JOURNAL)

SUMMARY

While the main pathogenic effect is mediated by autoantibodies against BP180, the pathogenic effect of anti-BP230 IgG has also recently been described in_vivo. In bullous pemphigoid (A), linear IgA disease, mucous membrane pemphigoid, pemphigoid gestationis, as well multiple_sclerosis and Alzheimer's disease (B) are depicetd. Together with the observation that antiBP230 IgG alone is . . .

 



If you want to have access to all the content you need to log in!

Thanks :)

Username or E-mail:

If you don't have an account, you can create one here.