Tyrosine dephosphorylation of the syndecan-1 pdz binding domain regulates syntenin-1 recruitment*

HIGHLIGHTS

  • who: Be̕atrice Sulka from the (UNIVERSITY) have published the paper: Tyrosine Dephosphorylation of the Syndecan-1 PDZ Binding Domain Regulates Syntenin-1 Recruitment*, in the Journal: (JOURNAL) of April/17,/2009
  • what: The authors report for the first time that syndecan-1 is 6A), consistent with the hypothesis that syntenin-1 recruit- rapidly tyrosine-dephosphorylated upon cell adhesion. The authors show that knocking-down syntenin-1 expression dramatically reduced the formation of microspikes in these adhered cells. As syntenin-1 was shown to play a role in the formation of actin-dependent cell adhesion . . .

     

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