Ubiquitin ligase activity inhibits cdk5 to control axon termination

HIGHLIGHTS

  • who: Muriel Desbois and collaborators from the Center for Integrative Brain Research, Seattle Children`s Research Institute, Seattle, Washington, United States of, Molecular and Cellular Biology Graduate Program, University of Washington, Seattle have published the research work: Ubiquitin ligase activity inhibits Cdk5 to control axon termination, in the Journal: (JOURNAL) of September/10,/2021
  • what: The authors show that Cdk5 is regulated by ubiquitin ligase activity in the nervous PLOS Genetics | https://doi.org/10.1371/journal.pgen . The authors show that the RPM-1/FSN-1 ubiquitin ligase complex restrains CDK-5 kinase activity . . .

     

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