Ubiquitin-specific peptidase 8 modulates cell proliferation and induces cell cycle arrest and apoptosis in breast cancer by stabilizing estrogen receptor alpha

HIGHLIGHTS

  • who: Stabilizing Estrogen Receptor Alpha et al. from the Department of Tyroid and Breast Surgery, Zhongnan Hospital of Wuhan University, Donghu Road, Wuhan, Hubei, China have published the paper: Ubiquitin-Specific Peptidase 8 Modulates Cell Proliferation and Induces Cell Cycle Arrest and Apoptosis in Breast Cancer by Stabilizing Estrogen Receptor Alpha, in the Journal: Journal of Oncology of 14/Dec/2022
  • what: The authors aimed to explore the role of ubiquitin-specifc peptidase 8 (USP8) in ERu03b1 signaling and identify potential targets for endocrine resistance. The study demonstrates that USP8 might be crucial in BC . . .

     

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