HIGHLIGHTS
- who: Angu00e8le Luby and Marie-Clotilde Alves-Guerra from the Universitu00e9 Paris Citu00e9, Institut Cochin, INSERM, CNRS, Paris, France have published the research: UCP2 as a Cancer Target through Energy Metabolism and Oxidative Stress Control, in the Journal: (JOURNAL)
- what: Cancer can be initiated by an uncontrolled accumulation of ROS, and then cancer cells survive and proliferate until they invade other organs by metabolic and immune reprogramming.
SUMMARY
By establishing xenografts with B16-OVA and YUMM1 melanoma cell lines with doxycycline-inducible UCP2 expression, they demonstrated that UCP2 overexpression in these . . .
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