Ultra-sensitive molecular detection of gene fusions from rna using aspyre

HIGHLIGHTS

  • who: Gray et_al BMC Medical and collaborators from the (UNIVERSITY) have published the research work: Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE, in the Journal: (JOURNAL)
  • what: The authors show further capabilities of the ASPYRE technology by detecting gene fusions from RNA, showing single-molecule detection limits equivalent to DNA, scaling to over 30 fusion targets from one initial RTPCR amplification reaction. The authors show detection of targets in commercially sourced synthetic samples, with detection down to single molecule copy numbers. Detection of gene fusions from patient tissue-derived RNA Finally . . .

     

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