HIGHLIGHTS
- who: Yoon-Seok Kim et al. from the All animal experiments were conducted according to the guidelines of the Institutional Animal Care and Use Committee (IACUC) of Seoul National University Bundang Hospital (approval number: MSRI-51-19-011, April, )ICR mice (, weeks old) were prepared for the pharmacokinetic studies. Mice were grouped into the free-DOX and , groups and injected intravenously with the respective drug preparation. Blood samples were collected at different time points (2, , , , , and , min). DOX was quantitatively measured in blood plasma. Briefly, mouse plasma mixed with DOX solution was prepared as a standard solution . . .
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