Unbiased characterization of peptide-hla class ii interactions based on large-scale peptide microarrays; assessment of the impact on hla class ii ligand and epitope prediction

HIGHLIGHTS

  • who: Mareike Wendorff and Andre Franke from the Weill Cornell Medicine, United States Genetics and Bioinformatics, Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany have published the research work: Unbiased Characterization of Peptide-HLA Class II Interactions Based on Large-Scale Peptide Microarrays; Assessment of the Impact on HLA Class II Ligand and Epitope Prediction, in the Journal: (JOURNAL)
  • what: The authors describe the results of applying two machine-learning frameworks to mine and extract the rules for peptide-HLA binding from the chip data, and the authors assess the quality . . .

     

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