Uncertainties in pentose-phosphate pathway flux assessment underestimate its contribution to neuronal glucose consumption: relevance for neurodegeneration and aging

HIGHLIGHTS

• who: Anne-Karine Bouzier-Sore and Juan P. Bolaños from the CentreUniversity of Salamanca, Spain have published the paper: Uncertainties in pentose-phosphate pathway flux assessment underestimate its contribution to neuronal glucose consumption: relevance for neurodegeneration and aging, in the Journal: (JOURNAL)

SUMMARY

Labeling in 13 C-Ru5P and 13 C-R5P ([2-13 C]-, -, -, etc.) after the second PPP round can be used for an accurate estimation of PPP in highly recycling cells. from_[1-14 C]glucose and that from_[6-14 C]glucose represents the flux of 14 CO2 . . .

 



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