Uncoupling the hydrolysis of lipid-linked oligosaccharide from the oligosaccharyl transfer reaction by point mutations in yeast oligosaccharyltransferase

HIGHLIGHTS

  • who: Takahiro Yamasaki from the Takahiro Yamasaki and Daisuke Kohda* From the Division of Structural Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan Edited by Gerald WHart have published the article: Uncoupling the hydrolysis of lipid-linked oligosaccharide from the oligosaccharyl transfer reaction by point mutations in yeast oligosaccharyltransferase, in the Journal: (JOURNAL) of June/29,/2020
  • how: The raw chromatographic data are presented in Fig S3.
  • future: The authors found that mutations in the first DXD motif increased the FNG generation activity relative to the oligosaccharyl transfer activity both in_vitro and . . .

     

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