Uncovering a 500 million year old history and evidence of pseudogenization for tlr15

HIGHLIGHTS

  • who: Fabiana Neves and collaborators from the Kagawa University, Japan have published the research work: Uncovering a 500 million year old history and evidence of pseudogenization for TLR15, in the Journal: (JOURNAL)
  • what: The authors focus specifically on TLR15 to confirm its origin in a gnathostome ancestor (~450 mya) and survey its presence in an ample set of vertebrate lineages, making use of available genomic and transcriptomic resources. The authors show that TLR15 is under overall negative selection (Supplementary Figure 1; Supplementary Table 3), probably to maintain the protein conformation and biological role with a . . .

     

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