Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with subtype and stage inference

HIGHLIGHTS

• who: Alexandra L Young from the (UNIVERSITY) have published the paper: Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors demonstrate SuStaIn using structural magnetic_resonance imaging (MRI) data sets from cohorts of genetic FTD and AD patients. In both neurodegenerative diseases, the authors demonstrate strong assignment of individuals to the SuStaIn subtypes, which is in contrast to subtypesonly models in the literature (e_g ref 23). In AD, the authors show that SuStaIn subtype and stage enhance the ability to predict . . .
  

   

  

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