Uncovering the mechanism of drug resistance caused by the t790m mutation in egfr kinase from absolute binding free energy calculations

HIGHLIGHTS

• who: Calculations and collaborators from the Research Center for Analytical Sciences, Frontiers Science Center for New Organic Matter, College of Chemistry, Key Laboratory of Biosensing and Molecular Recognition, State Key Laboratory of Medicinal Chemical Biology, Nankai University, China, Haihe Laboratory of Sustainable Chemical Transformations, China have published the article: Uncovering the Mechanism of Drug Resistance Caused by the T790M Mutation in EGFR Kinase From Absolute Binding Free Energy Calculations, in the Journal: (JOURNAL)
• what: This study shows the essential reason for the drug resistance induced by the May 2022 | Volume 9 | Article 922839 Absolute Binding . . .
  

   

  

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