HIGHLIGHTS
- who: Jodie Deborah Ouahed from the University of Colorado Anschutz Medical Campus, United States have published the research work: Understanding inborn errors of immunity: A lens into the pathophysiology of monogenic inflammatory bowel disease, in the Journal: (JOURNAL)
- what: Herein, a selection of IEI is presented, highlighting how interruption of various components of immunity contribute to IBD development.
- future: Studies are necessary to delineate mechanisms and cellular components whereby STXBP2 and STXBP3 maintain mucosal homeostasis.
SUMMARY
Disruption of the epithelial barrier can be subdivided into: defects in epithelial organization . . .
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