Understanding the combined effects of high glucose induced hyper-osmotic stress and oxygen tension in the progression of tumourigenesis: from mechanism to anti-cancer therapeutics

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  • who: Gayathri K. G. and colleagues from the Laboratory of Translational Mechanobiology, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India have published the paper: Understanding the Combined Effects of High Glucose Induced Hyper-Osmotic Stress and Oxygen Tension in the Progression of Tumourigenesis: From Mechanism to Anti-Cancer Therapeutics, in the Journal: Cells 2023, 825 of 17/02/2023
  • what: The primary reasons for treatment failure are due to rapidly expanding tumour heterogeneity and recurrence, chemo- and radio-resistance, oncogenic mutations, alternative splice variants, gene polymorphisms and rapid chromatin remodelling, all of which have posed . . .

     

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