HIGHLIGHTS
- who: K Liu from the State Key Laboratory Graduate University, Yulin, China have published the article: Understanding the roadmaps to induced pluripotency, in the Journal: (JOURNAL)
- what: Long induction periods and only small initiating populations of reprogrammable cells are two major hurdles in understanding the detailed molecular mechanisms of reprogramming.
SUMMARY
To resolve potential cancer risks associated with viral integration, integration-free iPSC production techniques were widely developed as the secondary generation of reprogramming approaches. So far, iPSCs without exogenous DNA integration have been generated using different strategies, including piggyBac transposition . . .
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