Understanding tricky cellular and molecular interactions in pancreatic tumor microenvironment: new food for thought

HIGHLIGHTS

  • who: Antonio Agostini from the Orientale, Italy University of Pennsylvania have published the article: Understanding Tricky Cellular and Molecular Interactions in Pancreatic Tumor Microenvironment: New Food for Thought, in the Journal: (JOURNAL)
  • what: The authors showed that the deserted subTME has a chemoprotective role, associated with a poor response, leading to the conclusion that future approaches aimed to attenuate the deserted TME state could be able to improve therapy outcome. aggressive disease . Probably, the main reason is that the authors are still missing many pieces of knowledge about the complex interactions happening in the ECM . . .

     

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