Unequivocal evidence for endogenous geranylgeranoic acid biosynthesized from mevalonate in mammalian cells[s]

HIGHLIGHTS

  • who: Yoshihiro Shidoji from the University of Nagasaki, Japan have published the Article: Unequivocal evidence for endogenous geranylgeranoic acid biosynthesized from mevalonate in mammalian cells[S], in the Journal: (JOURNAL)
  • what: In the first part of the present study, the authors demonstrate unequivocal evidence that endogenous GGA exists in several organs of male rats using LC/MS/MS. The second part of this study shows the metabolic labeling of endogenous GGA with a stable 13C isotope from 13C-mevalonolactone (MVL) in a human hepatoma-derived HuH-7 cell line. Before the observations of this study . . .

     

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