Unexpected cardiorespiratory findings postictally and at rest weeks prior to sudep

HIGHLIGHTS

SUMMARY

    Interictal HRV analysis showed that all sleep HRV parameters and most awake HRV parameters of the SUDEP patient were significantly lower than those of the two control subjects with bitemporal lobe epilepsy without SUDEP (p and amp;lt; 0.01). In two focal with impaired awareness seizures (FIAS) of the SUDEP patient, increased postictal mean HR and reduced preictal mean high frequency signals (HF), known markers of increased seizure severity in convulsive seizures, were seen postictally. Important autonomic instability and hypersensitivity were seen through fluctuations in LF/HF ratio following two seizures of the . . .

     

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