Unexpected gating behaviour of an engineered potassium channel kir

HIGHLIGHTS

  • who: Charline Fagnen and collaborators from the University of Trieste, Trieste, Italy, IBS University Grenoble Alpes, CNRS, CEA, Grenoble, France, Faculté have published the article: Unexpected Gating Behaviour of an Engineered Potassium Channel Kir, in the Journal: (JOURNAL)
  • what: If the authors compare the closed state of KirBac3.1 and the open state of KirBac3.1 S129R, the latter shows slightly more pronounced flexibility with a maximum value for the HDX of 68% ± 2.2 (Mean ± S.D n 3) against 59.1% ± 2.5 for the closed state as shown in Figure 2C.
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