Unique type i interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection

HIGHLIGHTS

  • who: Bruno Moltedo et al. from the Editor: Karen LMossman, McMaster University, Canada have published the Article: Unique Type I Interferon Responses Determine the Functional Fate of Migratory Lung Dendritic Cells during Influenza Virus Infection, in the Journal: (JOURNAL) of April/20,/2011
  • what: In these experiments the authors show that both subpopulations can become infected and migrate to the draining MLN but a difference in their response to type I interferon (I-IFN) signaling dictates the capacity of the virus to replicate. The authors demonstrate a striking dichotomy in the sensitivity to I-IFN . . .

     

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