HIGHLIGHTS
- who: Yuda Chen from the (UNIVERSITY) have published the research: Unleashing the potential of noncanonical amino acid biosynthesis to create cells with precision tyrosine sulfation, in the Journal: (JOURNAL) of 21/03/2022
- what: The authors report the creation of autonomous cells, both prokaryotic and eukaryotic, with the ability to biosynthesize and genetically encode sulfotyrosine (sTyr), an important protein post-translational modification with low membrane permeability. To identify the enzyme responsible for sulfation of cytoplasmic tyrosine, the authors focused on SULTs.
- how: To generate a suppression plasmid for sTyr incorporation the authors used . . .
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