HIGHLIGHTS
- What: Purpose: This research investigated the development of short hairpin RNA (shRNA) molecules designed to target specific regions of the HRSV and F genes. The study aimed to assess the of these shRNAs and evaluate the effectiveness of Tat peptide-mediated in enhancing their functionality. This study explores using shRNAs to target the virus and prevent replication. The study demonstrates that shRNAs targeting M and F genes effectively inhibit HRSV replication in Hep-2 cells, with combination therapy with ribavirin offering even greater efficacy.
- Who: Saket from the University of Medical, Shiraz, Iran have published . . .
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