Unraveling presenilin 2 functions in a knockout zebrafish line to shed light into alzheimer’s disease pathogenesis

HIGHLIGHTS

  • who: Lucia Barazzuol et al. from the Department of Biomedical Sciences, University of Padova, Padua, Italy have published the research work: Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimeru2019s Disease Pathogenesis, in the Journal: Cells 2023, 12, 376. of /2023/
  • what: The aim of the majority of the published studies on these stable psen2 mutant zebrafish lines was to identify the cellular processes affected by familial AD-linked mutations in young adult heterozygous mutant brains (specifically searching for an early familial AD brain transcriptomic signature). Genetic compensation may result . . .

     

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