Unraveling structural alerts in marketed drugs for improving adverse outcome pathway framework of drug-induced qt prolongation

HIGHLIGHTS

  • who: Wulin Long et al. from the College of Chemistry, Sichuan University, Chengdu, China have published the article: Unraveling Structural Alerts in Marketed Drugs for Improving Adverse Outcome Pathway Framework of Drug-Induced QT Prolongation, in the Journal: (JOURNAL) of 22/02/2023
  • what: Although the unexpected blockade of ion channels has been widely considered to be one of the main reasons for affecting the repolarization phase of the cardiac action potential and leading to interval the lack of knowledge regarding chemical structures in drugs that may induce the of the interval remains a barrier . . .

     

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