Unraveling the epigenomic and transcriptomic interplay during alcohol-induced anxiolysis

HIGHLIGHTS

  • who: Harish R. Krishnan from the (UNIVERSITY) have published the article: Unraveling the epigenomic and transcriptomic interplay during alcohol-induced anxiolysis, in the Journal: (JOURNAL) of 12/09/2022
  • what: The authors sought to investigate this question by utilizing two genome-wide approaches: Assay for Transposase-Accessible Chromatin with high throughput sequencing (ATAC-seq), which identifies changes in genome accessibility, and RNA-seq, which assesses changes in global gene_expression following acute ethanol . This study has identified epigenomic and transcriptomic changes in the amygdala produced by acute ethanol exposure as well as a candidate gene, Hif3a . . .

     

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