Unraveling the link between interferon- and systemic lupus erythematosus: from the molecular mechanisms to target therapies

HIGHLIGHTS

  • who: Barbara Infante et al. from the Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy have published the research: Unraveling the Link between Interferon- and Systemic Lupus Erythematosus: From the Molecular Mechanisms to Target Therapies, in the Journal: (JOURNAL)
  • what: Type-I-interferons production is affected by interactions between plasmacytoid DC and many other cell types as well as environmental factors.

SUMMARY

    The hyperactivation of antigen presenting cells (APCs) results in the incorrect recognition of autoantigens and to an activation of mature autoreactive B-cells. There is evidence . . .

     

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