HIGHLIGHTS
- who: Vikas Maurya from the Nehru University are purchased from National Collection of Type Cultures, public health England have published the research work: Unraveling topoisomerase IA gate dynamics in presence of PPEF and its preclinical evaluation against multidrug-resistant pathogens, in the Journal: (JOURNAL) of 12/05/2022
- what: The authors investigated the mechanism of two synthetic antibacterial molecules targeting TopoI of S. aureus (SaTopoIA) A. baumannii (AbTopoIA) and E. coli (EcTopoIA and EcTopoIII) which are vital for DNA replication thereby preventing the multiplication and dispersion of the bacteria. The authors showcase a successful development . . .
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