Unveiling il-33/st2 pathway unbalance in cardiac remodeling due to obesity in zucker fatty rats

HIGHLIGHTS

  • who: Clementina Sitzia and collaborators from the Department of Biomedical Science for Health, Medical Faculty, University of Milan, Milan, Italy have published the research work: Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats, in the Journal: (JOURNAL) of 16/01/2023
  • what: The authors aimed to investigate cardiac remodeling in obesity, both in_vivo and in_vitro, and-in particular-to study the pathways linking ectopic fat accumulation and detrimental fibrotic remodeling of the heart. Among the mediators of cardiac remodeling, the authors focused on Epac proteins (Epac 1 . . .

     

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