Unweaving the mitotic spindle: a focus on aurora kinase inhibitors in lung cancer

HIGHLIGHTS

  • who: Alessio Stefani from the Division of Experimental Thoraco Pulmonary (IRCCS), Italy University of Naples II, Italy have published the paper: Unweaving the mitotic spindle: A focus on Aurora kinase inhibitors in lung cancer, in the Journal: (JOURNAL)
  • what: The study included 26 patients with NSCLC and an objective response (OR) was registered in just 1 (4%, 0-22) of 23 evaluable patients, while 17 (74%, 52-90) achieved a stable disease (SD).

SUMMARY

    In mammals, there are three known members of this family: Aurora kinase A (AURKA), Aurora kinase B . . .

     

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