Up-regulation, modification, and translocation of s100a6 induced by exposure to ionizing radiation revealed by proteomics profiling*

HIGHLIGHTS

  • who: Up-regulation and collaborators from the Karolinska University have published the Article: Up-regulation, Modification, and Translocation of S100A6 Induced by Exposure to Ionizing Radiation Revealed by Proteomics Profiling*, in the Journal: (JOURNAL)
  • what: The authors report here an increase in S100A6 protein level in colon and lung cancer cells postexposure to ionizing_radiation. This p53-potentiated ROS formation could explain the p53-dependent differences in S100A6 protein level and modification pattern the authors report postirradiation.
  • how: The shift from glutathionylation to cysteinylation that the authors showed in this study is previously unknown . . .

     

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