Upcoming pharmacological developments in chronic hepatitis b: can we glimpse a cure on the horizon?

HIGHLIGHTS

  • who: Sonia Alonso from the (UNIVERSITY) have published the research work: Upcoming pharmacological developments in chronic hepatitis B: can we glimpse a cure on the horizon?, in the Journal: (JOURNAL)
  • what: Recent developments of new highly effective antiviral therapy against HCV infection have fueled the research for a cure of chronic HBV infection or HBsAg loss.

SUMMARY

    NAs (Entecavir and Tenofovir), inhibit the HBV polymerase activity and thus viral_replication, but with no major impact on cccDNA which is used to transcribe viral RNAs. The vast majority of patients require lifelong treatment . . .

     

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