Upf3a is dispensable for nonsense-mediated mrna decay in mouse pluripotent and somatic cells

HIGHLIGHTS

  • who: Chengyan Chen and collaborators from the State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany have published the paper: UPF3A is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cells, in the Journal: (JOURNAL)
  • what: The authors named these cell lines as RDSCs (Rib muscle derived somatic_cells). qPCR and Western blot analysis showed that 5 d of 4-OHT treatment successfully depleted UPF3A in RDSCs (Fig 1C, lower panel; Figs 1D, 2B, and S3A).
  • how: In the analysis previously . . .

     

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