Upper respiratory infection drives clinical signs and inflammatory responses following heterologous challenge of sars-cov-2 variants of concern in k18 mice

HIGHLIGHTS

  • who: Jacob H. Nichols and colleagues from the Department of Microbiology, Immunology and Biochemistry, College of Medicine, University of Tennessee Regional Biocontainment Laboratory, University of Tennessee Health Science Center, Memphis, TN, USA have published the research: Upper Respiratory Infection Drives Clinical Signs and Inflammatory Responses Following Heterologous Challenge of SARS-CoV-2 Variants of Concern in K18 Mice, in the Journal: Viruses 2023, 15, 946. of 30/03/2023
  • what: The authors report that an infection with a low dose of SARS-CoV-2 confers significant protection from challenge, but mice in the heterologous challenge . . .

     

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