Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury

HIGHLIGHTS

  • who: Jason L. Chang from the Division of Biology and Medicine, Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Meeting Street, SFH, Providence, RI, USA have published the Article: Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury, in the Journal: (JOURNAL)
  • what: The authors show that upregulating Cpt1a by l-carnitine or baicalin ameliorates neonatal hyperoxia-induced persistent alveolar and vascular simplification in adult mice.
  • how: These experiments were carried out in a blinded manner.
  • future: Study is required to determine whether l . . .

     

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