Upregulation of galnt7 in prostate cancer modifies o-glycosylation and promotes tumour growth

HIGHLIGHTS

  • who: Emma Scott from the (UNIVERSITY) have published the article: Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth, in the Journal: (JOURNAL) of 22/09/2022
  • what: The authors show GALNT7 is found in diagnostically relevant levels in the urine and blood of men with prostate cancer. Using lectin/antibody immunoassays, chemical tools and O-glycoproteomics, the authors show GALNT7 modifies O-glycoproteins in prostate cancer cells, and using both in_vitro and in_vivo studies, the authors further show that GALNT7 drives prostate tumour growth and correlates with cell cycle and . . .

     

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