Upregulation of key genes eln and tgfb3 were associated with the severity of cardiac hypertrophy

HIGHLIGHTS

• who: Rui Zhang from the between the brachiocephalic trunk and left common carotid artery were dissected and tied around the aorta against a, gauge needle, then ligated with a , , nylon sutureThe sham group mice were subjected to thoracotomy and aortic dissection without constricting the aorta. After surgery, the mice were housed at appropriate temperature and humidity, and maintained a , h dark-light cycle with free availability of food and water lasting for , weeks. Totally, there were , mice included in this study and equally divided into two groups. The animal study was approved by the Animal Ethics Committee . . .
  

   

  

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