Upregulation of spinal mir-155-5p contributes to mechanical hyperalgesia by promoting inflammatory activation of microglia in bone cancer pain rats

HIGHLIGHTS

• who: Yanping Jian et al. from the Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, China have published the article: Upregulation of Spinal miR-155-5p Contributes to Mechanical Hyperalgesia by Promoting Inflammatory Activation of Microglia in Bone Cancer Pain Rats, in the Journal: Life 2022, 1349 of 30/08/2022
• what: The authors attempted to verify the role of microglial activation in the spinal cord of BCP rats. The study provided the novel insight that the miR-155-5p/Sgk3/microglia axis could be an important regulatory mechanism in BCP development and might . . .
  

   

  

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