Uptake and processing of the cytolethal distending toxin by mammalian cells

HIGHLIGHTS

  • who: Joseph M. DiRienzo from the Department of Microbiology, School of Dental Medicine, University of Pennsylvania have published the article: Uptake and Processing of the Cytolethal Distending Toxin by Mammalian Cells, in the Journal: Toxins 2014, 6, 3098-3116 of 19/09/2014
  • what: The aim of this review is to present current information about the mechanisms of uptake and translocation of the Cdt in relation to standard concepts of endocytosis and retrograde transport.
  • how: This process is exploited by some AB toxins such as cholera and Pseudomonas exotoxin A to reach the . . .

     

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