Ursodeoxycholic acid influences the expression of p27 but not foxo1 in patients with non-cirrhotic primary biliary cirrhosis

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  • who: King's from the Medical Biology Laboratory, Pomeranian Medical University, Aleja Powstancow Wlkp72, Szczecin, Poland have published the paper: Ursodeoxycholic Acid Influences the Expression of p27 but Not FoxO1 in Patients with Non-Cirrhotic Primary Biliary Cirrhosis, in the Journal: (JOURNAL) of 12/Nov/2013
  • what: Knowing that hepatocytes are able to arrest reversibly a cell growth, the authors focused on the genes that repeatedly correlate with modulation of the cell cycle. The authors demonstrated an enhanced expression of p27kip1 mRNA in non-cirrhotic and cirrhotic PBC livers and noted that the level of . . .

     

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