HIGHLIGHTS
- who: Christof Taxis from the (UNIVERSITY) have published the research work: Use of Modular Substrates Demonstrates Mechanistic Diversity and Reveals Differences in Chaperone Requirement of ERAD*, in the Journal: (JOURNAL) of January/31,/2003
- what: The current model for ERAD has evolved over the past 20 years and is based on data accumulated using a wide range of substrates with different structural and functional characteristics studied in different eukaryotic systems. The authors show that the breakdown of soluble CPY* or of the membrane-bound variant CT* is also independent of Hsp70 chaperones of the Ssa . . .
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