Using big data analytics to “back engineer” protein conformational selection mechanisms

HIGHLIGHTS

  • who: Shivangi Gupta et al. from the Department of Computer Science, The University of Alabama in Huntsville, Huntsville, AL, USA have published the research work: Using Big Data Analytics to u201cBack Engineeru201d Protein Conformational Selection Mechanisms, in the Journal: Molecules 2022, 27, 2509. of /2022/
  • what: The authors are aiming to understand why these rare apo-conformations possess this capacity to bind their ligands, while the vast majority of the other protein conformations do not. There are fundamental issues that are specific to the field of Big Data analytics that the authors aim at addressing . . .

     

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