HIGHLIGHTS
- who: Mark Reppell and John Novembre from the Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America have published the research work: Using pseudoalignment and base quality to accurately quantify microbial community composition, in the Journal: (JOURNAL) of April/16,/2018
- what: The authors propose a novel method for taxonomic profiling in pooled DNA that combines the speed and low-memory requirements of k-mer based pseudoalignment with a likelihood framework that uses base quality information to better resolve multiply mapped reads. Using simulations the authors show the method is accurate . . .
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